The 10K Run starts at Perimeter Drive near the Lyric Theatre, and follows Perimeter Drive Southeast, then towards the beautiful Formal Garden. It continues out to the corner of Corydon Avenue and Park Boulevard, turning down Park Boulevard to Wellington Crescent. Be sure to keep your eyes on the prize and not the beautiful houses (or the canker worms trying to land on your face). Runners will then head east on Wellington Crescent to Guelph Street, looping back west along Wellington Crescent to the finish line in Assiniboine Park. The route is certified and sanctioned, and is wheelchair accessible.
You can register for the event here. Cost is $43 but you get a free Runnning Room T-shirt and a commemorative medal.
Check out their site to get more details.